[Fiware-opencall-help] BIOTEM : Expert en humanisation d'anticorps

BIOTEM : Custom Antibodies and Services services at biotem-info.com
Wed Mar 15 11:28:44 CET 2017


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(http://www.biotem-antibody.com/)


MurineAntibody 
(http://www.biotem-antibody.com/mouse-monoclonal-antibody-development-production/p34.html)
|  Rabbit Antibody (http://www.biotem-antibody.com/rabbit-monoclonal-antibody-development-production/p65.html)   |   Immunoassays  (http://www.biotem-antibody.com/immunoassay-development-production/p35.html) | Therapeutic Ab (http://www.biotem-antibody.com/antibody-engineering-therapy/p57.html) |  Additionalservices (http://www.biotem-antibody.com/cell-banking-hybridoma-sequencing-mycoplasma/p38.html) 


ANTIBODY HUMANISATION
BIOTEM solutions to optimise your therapeutic antibody! 


SEE OUR 100% ROYALTY FREE PROCESS IN 3 STEPS



Identification of antibody domains and critical residues for antigen binding
Parental Antibody Analysis - Bioinformatic Analysis - 3D structure modeling 


Combination of the parental CDRs (complementarity determining regions) 
with human germline framework regions

* Validation of optimal Human frameworks(VH/VL pairing) with 100 % affinity retainedImproving further the Germinality Index(GI or % of humanness)


Substitutions of amino-acid prone to post-translational modifications and/or amino acid combinations that may lead to antibody denaturation 
Antibody tolerance in humans - Manufacturability  -Drugability-Affinity(potentially)
 



Learn more
(http://www.biotem-antibody.com/humanized-antibody-development-production/p59.html)



TESTIMONIALS


Find all our services on: www.biotem-antibody.com (http://www.biotem-antibody.com/)  
 Contact our Technical Team for further information


CONTACT BIOTEM's TEAM


Parc d’activités Bièvre Dauphine 
885, rue Alphonse Gourju 
38140 Apprieu – France

 info at biotem.fr (mailto:info at biotem.fr) 

 +33 (0)4 76 65 10 91 


 (https://twitter.com/biotem_antibody)  (mailto:<info at biotem.fr>)  (https://www.linkedin.com/company/biotem-custom-antibodies-&-services) 

If you do not wish to receive discount offers and/or information about our latest technologies please click here
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